The Sixers will be without both Nerlens Noel and Jahlil Okafor in tonight's preseason game against the Knicks at Madison Square Garden.
Noel will miss his second straight game with knee and back injuries suffered last Thursday against Cleveland.
Okafor is out with a sore knee. He scored just two points on 1 for 6 shooting in Saturday's win over Brooklyn.
The Sixers will start Isaiah Canaan and JaKarr Sampson at guard, and three forwards in Robert Covington, Jerami Grant and rookie Richaun Holmes.
The Sixers are 2-1 this preseason. After facing the Knicks tonight, they host the Wizards on Friday, play the Nets in Brooklyn on Sunday and finish the preseason next Friday in Boston against the Celtics.